SCHEMBL31707374

SCHEMBL31707374

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nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 2/20 0.38
▸ BACE1 P56817 4/20 0.37
▸ ECE1 P42892 3/20 0.36
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ ITGB2 P05107 1/20 0.34
▸ ICAM1 P05362 1/20 0.34
▸ ITGAL P20701 1/20 0.34
▸ GNPAT O15228 1/20 0.34
▸ ENPEP Q07075 3/20 0.34
▸ OPRD1 P41143 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30798035 0.95 MME (0.41) MMEECE1GNPATENPEP
SCHEMBL29373629 0.94 ECE1 (0.39) MMEBACE1ECE1MEN1KMT2A
SCHEMBL30192164 0.93 BACE1 (0.36) MMEBACE1ECE1ITGB2ICAM1
SCHEMBL30477911 0.93 MME (0.39) MMEECE1GNPATENPEPOPRD1
SCHEMBL29360643 0.93 MME (0.42) MMEECE1GNPATENPEP
SCHEMBL31596910 0.92 BACE1 (0.47) BACE1OPRD1
SCHEMBL29510840 0.92 MME (0.38) MMEBACE1GNPATENPEP
SCHEMBL30859432 0.92 MME (0.40) MMEECE1GNPATENPEP
SCHEMBL30973091 0.91 BACE1 (0.43) BACE1ENPEPOPRD1
SCHEMBL29913867 0.91 ECE1 (0.36) MMEBACE1ECE1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583922-B2 Bispecific antibodies targeting CD47 and PD-L1 and methods of use thereof NOVIMMUNE SA (CH) 2026-03-24 — — US claimed
US-12448444-B2 Bispecific antibodies targeting CD47 and PD-L1 and methods of use thereof NOVIMMUNE SA (CH) 2025-10-21 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583922-B2 Bispecific antibodies targeting CD47 and PD-L1 and methods of use thereof CD47, PDCD1LG2, CD274 MME 4248/4885BACE1 2025/4885ECE1 3640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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