Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 1.00 |
| ▸ | FLT3 | P36888 | 3/20 | 1.00 |
| ▸ | BLK | P51451 | 2/20 | 1.00 |
| ▸ | JAK3 | P52333 | 1/20 | 0.80 |
| ▸ | BTK | Q06187 | 6/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16680603 | 1.00 | EGFR (1.00) | EGFRFLT3BLKJAK3BTK | |
| SCHEMBL30353469 | 0.93 | EGFR (0.87) | EGFRFLT3BLKJAK3BTK | |
| SCHEMBL18294430 | 0.93 | EGFR (0.87) | EGFRFLT3BLKJAK3BTK | |
| SCHEMBL18294436 | 0.93 | EGFR (0.87) | EGFRFLT3BLKJAK3BTK | |
| SCHEMBL30353489 | 0.93 | EGFR (0.87) | EGFRFLT3BLKJAK3BTK | |
| SCHEMBL16693941 | 0.93 | EGFR (1.00) | EGFRFLT3BLKJAK3BTK | |
| SCHEMBL18294441 | 0.93 | EGFR (0.86) | EGFRFLT3BLKJAK3BTK | |
| SCHEMBL29572941 | 0.93 | EGFR (0.86) | EGFRFLT3BLKJAK3BTK | |
| SCHEMBL18294440 | 0.93 | EGFR (0.86) | EGFRFLT3BLKJAK3BTK | |
| SCHEMBL30353468 | 0.93 | EGFR (0.86) | EGFRFLT3BLKJAK3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284747-A1 | NOVEL USE OF EGFR INHIBITOR | 上海汇伦医药股份有限公司 | 2023-01-19 | — | — | WO | disclosed |