Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832914 | 1.00 | EPHX2 (0.49) | EPHX2NR1H4KDM4AHDAC10HDAC6 | |
| SCHEMBL1495902 | 0.87 | EPHX2 (0.64) | EPHX2NR1H4KDM4AHDAC10HDAC6 | |
| SCHEMBL1495955 | 0.86 | EPHX2 (0.50) | EPHX2NR1H4KDM4ABDKRB1 | |
| SCHEMBL30193362 | 0.85 | EPHX2 (0.49) | EPHX2NR1H4KDM4AHDAC10HDAC6 | |
| SCHEMBL23832978 | 0.85 | EPHX2 (0.49) | EPHX2NR1H4KDM4AHDAC10HDAC6 | |
| SCHEMBL30739196 | 0.84 | EPHX2 (0.48) | EPHX2NR1H4KDM4AHDAC10HDAC6 | |
| SCHEMBL15729681 | 0.84 | EPHX2 (0.54) | EPHX2NR1H4KDM4AHDAC10HDAC6 | |
| SCHEMBL507345 | 0.84 | EPHX2 (0.48) | EPHX2NR1H4KDM4AHDAC10HDAC6 | |
| SCHEMBL21996281 | 0.83 | EPHX2 (0.43) | EPHX2NR1H4KDM4AKCNA5BDKRB1 | |
| SCHEMBL30739096 | 0.82 | EPHX2 (0.47) | EPHX2NR1H4KDM4AHDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121055-A1 | STAT DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |