Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.84 |
| ▸ | LMNA | P02545 | 5/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.80 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2243293 | 1.00 | MAPT (0.84) | MAPTKDM4ELMNASMN1; SMN2MAPK1 | |
| SCHEMBL19283314 | 0.90 | MAPT (0.78) | MAPTKDM4ELMNASMN1; SMN2MAPK1 | |
| SCHEMBL19283312 | 0.90 | MAPT (0.78) | MAPTKDM4ELMNASMN1; SMN2MAPK1 | |
| SCHEMBL12443146 | 0.89 | KDM4E (0.75) | MAPTKDM4ELMNASMN1; SMN2MAPK1 | |
| SCHEMBL683795 | 0.89 | MAPT (0.86) | MAPTKDM4ELMNASMN1; SMN2MAPK1 | |
| SCHEMBL13617293 | 0.89 | MAPT (0.86) | MAPTKDM4ELMNASMN1; SMN2MAPK1 | |
| SCHEMBL28295711 | 0.88 | MAPT (0.84) | MAPTKDM4ELMNASMN1; SMN2MAPK1 | |
| SCHEMBL12387732 | 0.86 | MAPT (0.75) | MAPTKDM4ELMNASMN1; SMN2MAPK1 | |
| SCHEMBL12387818 | 0.86 | MAPT (0.68) | MAPTKDM4ELMNASMN1; SMN2MAPK1 | |
| SCHEMBL12387950 | 0.86 | LMNA (0.73) | MAPTKDM4ELMNASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848441-B | N-substituted benzoyl hydrazone compound and preparation method and application thereof | 山东中新科农生物科技有限公司 | 2023-02-17 | — | — | CN | disclosed |