Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.60 |
| ▸ | DRD4 | P21917 | 5/20 | 0.60 |
| ▸ | DRD3 | P35462 | 5/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | DRD5 | P21918 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | HTR1D | P28221 | 1/20 | 0.60 |
| ▸ | HTR1B | P28222 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | HTR1E | P28566 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30193634 | 0.97 | HRH3 (0.64) | DRD2HRH3DRD4DRD3ADRB2 | |
| SCHEMBL30193406 | 0.95 | DRD2 (0.64) | DRD2HRH3DRD4DRD3ADRB2 | |
| SCHEMBL20029449 | 0.95 | DRD2 (0.71) | DRD2HRH3DRD4DRD3ADRB2 | |
| SCHEMBL30193808 | 0.91 | MAOB (0.60) | DRD2HRH3DRD4DRD3 | |
| SCHEMBL30193881 | 0.90 | DRD2 (0.66) | DRD2HRH3DRD4DRD3ADRB2 | |
| SCHEMBL31094010 | 0.90 | DRD2 (0.62) | DRD2HRH3DRD4DRD3ADRB2 | |
| SCHEMBL18496155 | 0.90 | DRD2 (0.62) | DRD2HRH3DRD4DRD3ADRB2 | |
| Hydrochloric Acid SCHEMBL18496124 | 0.89 | DRD2 (0.61) | DRD2HRH3DRD4DRD3ADRB2 | |
| Hydrochloric Acid SCHEMBL29922934 | 0.89 | DRD2 (0.61) | DRD2HRH3DRD4DRD3ADRB2 | |
| SCHEMBL30193620 | 0.89 | DRD2 (0.63) | DRD2HRH3DRD4DRD3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110776459-B | Cholinesterase inhibitors of 7-hydroxy-2-quinolone-dithiocarbamates | 江苏知原药业股份有限公司 | 2023-01-24 | — | — | CN | disclosed |