SCHEMBL30195037

SCHEMBL30195037

CCc1nccn1Cc1ccc(-c2cc(CC(C)C)sc2S(=O)(=O)Nc2ncccn2)cc1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 19/20 0.56
AGTR1 P30556 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30194918 0.89 AGTR2 (0.67) AGTR2AGTR1
SCHEMBL30195031 0.89 AGTR2 (0.56) AGTR2
SCHEMBL30195104 0.88 AGTR2 (0.54) AGTR2
SCHEMBL23831119 0.87 AGTR2 (0.66) AGTR2AGTR1
SCHEMBL30195071 0.87 AGTR2 (0.69) AGTR2
SCHEMBL30195163 0.85 AGTR2 (0.56) AGTR2
SCHEMBL23120730 0.83 AGTR2 (0.56) AGTR2AGTR1
SCHEMBL23121164 0.83 AGTR2 (0.58) AGTR2AGTR1
SCHEMBL30195045 0.83 AGTR2 (0.46) AGTR2AGTR1
SCHEMBL29106461 0.81 AGTR2 (0.84) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4367110-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS Vicore Pharma AB (SE) 2024-05-15 EP claimed
CN-117916229-A Novel selective angiotensin II compounds 维科尔药物公司 2024-04-19 CN claimed
WO-2023281271-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS VICORE PHARMA AB (SE) 2023-01-12 WO claimed
CN-117916229-A Novel selective angiotensin II compounds 维科尔药物公司 2024-04-19 CN disclosed
WO-2023281271-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS VICORE PHARMA AB (SE) 2023-01-12 WO disclosed