SCHEMBL30195044

SCHEMBL30195044

CC(C)Cc1ccc(S(=O)(=O)Nc2ncc(Cl)cn2)c(-c2ccc(Cn3ccnc3C(C)(C)C)cc2)c1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 14/20 0.48
EDNRA P25101 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30195061 0.93 AGTR2 (0.47) AGTR2EDNRA
SCHEMBL30195101 0.92 AGTR2 (0.51) AGTR2EDNRA
SCHEMBL30195081 0.92 AGTR2 (0.49) AGTR2
SCHEMBL30195054 0.92 AGTR2 (0.49) AGTR2EDNRA
SCHEMBL30195213 0.91 AGTR2 (0.52) AGTR2EDNRA
SCHEMBL30195008 0.91 AGTR2 (0.49) AGTR2EDNRA
SCHEMBL30195087 0.90 AGTR2 (0.47) AGTR2
SCHEMBL30195027 0.90 AGTR2 (0.49) AGTR2EDNRA
SCHEMBL23831144 0.86 AGTR2 (0.51) AGTR2
SCHEMBL30195074 0.85 AGTR2 (0.51) AGTR2EDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4367110-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS Vicore Pharma AB (SE) 2024-05-15 EP claimed
CN-117916229-A Novel selective angiotensin II compounds 维科尔药物公司 2024-04-19 CN claimed
WO-2023281271-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS VICORE PHARMA AB (SE) 2023-01-12 WO claimed
CN-117916229-A Novel selective angiotensin II compounds 维科尔药物公司 2024-04-19 CN disclosed
WO-2023281271-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS VICORE PHARMA AB (SE) 2023-01-12 WO disclosed