SCHEMBL30195079

SCHEMBL30195079

CC(C)Cc1cc(-c2ccc(Cn3ccnc3C(C)C)c(F)c2)c(S(=O)(=O)Nc2ncccn2)s1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 20/20 0.54
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30195019 0.91 AGTR2 (0.55) AGTR2CYP3A4
SCHEMBL30970239 0.90 AGTR2 (0.54) AGTR2CYP3A4
SCHEMBL30195104 0.89 AGTR2 (0.54) AGTR2
SCHEMBL30194917 0.89 AGTR2 (0.67) AGTR2CYP3A4
SCHEMBL25246111 0.89 AGTR2 (0.47) AGTR2CYP3A4
SCHEMBL25286142 0.89 AGTR2 (0.54) AGTR2CYP3A4
SCHEMBL30476533 0.89 AGTR2 (0.54) AGTR2CYP3A4
SCHEMBL25292058 0.88 AGTR2 (0.45) AGTR2CYP3A4
SCHEMBL29437919 0.88 AGTR2 (0.45) AGTR2CYP3A4
SCHEMBL30195038 0.87 AGTR2 (0.55) AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4367110-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS Vicore Pharma AB (SE) 2024-05-15 EP claimed
CN-117916229-A Novel selective angiotensin II compounds 维科尔药物公司 2024-04-19 CN claimed
WO-2023281271-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS VICORE PHARMA AB (SE) 2023-01-12 WO claimed
CN-117916229-A Novel selective angiotensin II compounds 维科尔药物公司 2024-04-19 CN disclosed
WO-2023281271-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS VICORE PHARMA AB (SE) 2023-01-12 WO disclosed