Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 4/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.34 |
| ▸ | CFB | P00751 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630413 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CYP2A6RAD51CSNK1DCSNK1A1 | |
| SCHEMBL16953034 | 0.84 | CYP2A6 (0.41) | ALDH1A1CYP2A6RAD51CSNK1DCSNK1A1 | |
| SCHEMBL29956134 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CYP2A6RAD51CSNK1DCSNK1A1 | |
| SCHEMBL28637754 | 0.80 | — | — | |
| SCHEMBL2460307 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CYP2A6RAD51CSNK1DCSNK1A1 | |
| SCHEMBL5613280 | 0.78 | RAD51 (0.40) | ALDH1A1CYP2A6RAD51CSNK1DCSNK1A1 | |
| SCHEMBL23835197 | 0.76 | RAD51 (0.39) | RAD51CSNK1DCSNK1G2CYP11B1CYP11B2 | |
| SCHEMBL31159880 | 0.76 | RAD51 (0.39) | RAD51CSNK1DCSNK1G2CYP11B1CYP11B2 | |
| SCHEMBL31750154 | 0.76 | MEN1 (0.42) | ALDH1A1CYP2A6RAD51CYP11B2EGLN2 | |
| SCHEMBL21162204 | 0.76 | AR (0.47) | ALDH1A1ARLRRK2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121425-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE | Akebia Therapeutics Inc. (US) | 2023-01-25 | — | — | EP | disclosed |