Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29307526 | 1.00 | CFTR (0.47) | CFTRKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4367290 | 0.86 | CACNA1B (0.42) | CFTRMEN1KMT2AMAPTRXRA | |
| SCHEMBL4369944 | 0.84 | CES2 (0.42) | CFTRMEN1KMT2AMAPTRXRA | |
| SCHEMBL30291804 | 0.84 | HDAC1 (0.43) | AAK1ALOX15 | |
| SCHEMBL4365064 | 0.84 | MEN1 (0.44) | MEN1KMT2AGAARXRANR1H2 | |
| SCHEMBL30196303 | 0.84 | CFTR (0.44) | CFTRKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29307533 | 0.84 | CFTR (0.44) | CFTRKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL31324581 | 0.81 | MAPT (0.51) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL29307527 | 0.81 | MAPT (0.51) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL30196890 | 0.80 | CFTR (0.42) | CFTRKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301100-A | Novel 1, 2-diaminobenzimidazole derivatives | 卡尔那生物科学株式会社 | 2025-01-10 | — | — | CN | disclosed |
| EP-4373811-A1 | NOVEL 1,2-DIAMINOBENZIMIDAZOLE DERIVATIVE | Carna Biosciences, Inc. (JP) | 2024-05-29 | — | — | EP | disclosed |
| WO-2023002246-A1 | NOVEL 1,2-DIAMINOBENZIMIDAZOLE DERIVATIVE | CARNA BIOSCIENCES, INC. (JP) | 2023-01-26 | — | — | WO | disclosed |