Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 7/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30672033 | 0.91 | AGTR2 (0.47) | AGTR2HDAC1CYP3A4 | |
| SCHEMBL30195046 | 0.79 | AGTR2 (0.44) | AGTR2 | |
| SCHEMBL30194995 | 0.78 | AGTR2 (0.45) | AGTR2 | |
| SCHEMBL29958663 | 0.78 | KCNH2 (0.40) | AGTR2CYP3A4 | |
| SCHEMBL23831153 | 0.76 | AGTR2 (0.50) | AGTR2 | |
| SCHEMBL30338037 | 0.76 | AGTR2 (0.50) | AGTR2 | |
| SCHEMBL23842521 | 0.74 | AGTR2 (0.47) | AGTR2CYP3A4 | |
| SCHEMBL25576375 | 0.74 | AGTR2 (0.59) | AGTR2CYP3A4 | |
| SCHEMBL23842522 | 0.74 | AGTR2 (0.59) | AGTR2CYP3A4 | |
| Potassium Ion SCHEMBL30394494 | 0.73 | AGTR2 (0.46) | AGTR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121165-A1 | NOVEL COMPOUNDS USEFUL IN THE TREATMENT AND/OR PREVENTION OF A DISEASE, DISORDER OR CONDITION ASSOCIATED WITH ANGIOTENSIN II | Vicore Pharma AB (SE) | 2023-01-25 | — | — | EP | disclosed |