SCHEMBL30196067

SCHEMBL30196067

O=[N+]([O-])c1ccccc1-c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
TDP1 Q9NUW8 4/20 1.00
CRHBP P24387 1/20 0.52
CRHR2 Q13324 1/20 0.52
S100A4 P26447 2/20 0.50
HSD17B10 Q99714 2/20 0.50
PTPN1 P18031 1/20 0.50
TSHR P16473 1/20 0.50
PTPRC P08575 1/20 0.50
ADAMTS4 O75173 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MGAM O43451 1/20 0.47
GAA P10253 1/20 0.47
SI P14410 1/20 0.47
MGAM2 Q2M2H8 1/20 0.47
MAPK1 P28482 2/20 0.47
TP53 P04637 1/20 0.47
CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28038982 1.00 ALDH1A1 (1.00) ALDH1A1TDP1CRHBPCRHR2S100A4
SCHEMBL44392 1.00 ALDH1A1 (1.00) ALDH1A1TDP1CRHBPCRHR2S100A4
Water SCHEMBL1828402 0.98 ALDH1A1 (0.96) ALDH1A1TDP1CRHBPCRHR2S100A4
Biphenyl SCHEMBL7209601 0.98 ALDH1A1 (0.96) ALDH1A1TDP1CRHBPCRHR2S100A4
Methane SCHEMBL2186810 0.98 ALDH1A1 (0.96) ALDH1A1TDP1CRHBPCRHR2S100A4
Water SCHEMBL2045405 0.98 ALDH1A1 (0.96) ALDH1A1TDP1CRHBPCRHR2S100A4
Hydrogen Sulfide SCHEMBL9671158 0.98 ALDH1A1 (0.96) ALDH1A1TDP1CRHBPCRHR2S100A4
SCHEMBL29180134 0.96 ALDH1A1 (0.92) ALDH1A1TDP1CRHBPCRHR2S100A4
SCHEMBL2958562 0.96 ALDH1A1 (0.92) ALDH1A1TDP1CRHBPCRHR2S100A4
Formaldehyde SCHEMBL28138834 0.96 ALDH1A1 (0.92) ALDH1A1TDP1CRHBPCRHR2S100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115715285-A Compounds as UBR box domain ligands 奧土择破利悟 2023-02-24 CN disclosed