Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30196076 | 0.81 | SLC6A2 (0.50) | CA12CA1CA2CA4CA7 | |
| SCHEMBL27863637 | 0.81 | SLC6A2 (0.50) | CA12CA1CA2CA4CA7 | |
| 1,2-Diethoxybenzene SCHEMBL10335108 | 0.69 | CA12 (0.65) | MAPTKDM4ECA12CA1CA2 | |
| 1-Methoxy-2-Ethoxybenzene SCHEMBL194473 | 0.69 | CA12 (0.65) | MAPTKDM4ECA12CA1CA2 | |
| SCHEMBL31078868 | 0.68 | HPGD (0.55) | MAPTTSHRHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1697616 | 0.68 | HPGD (0.55) | MAPTTSHRHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL12728608 | 0.68 | MAPT (0.48) | MAPTKDM4ETSHRHSD17B10CA12 | |
| SCHEMBL31045486 | 0.68 | MCHR1 (0.53) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL19144812 | 0.68 | KDM4E (0.51) | MAPTKDM4ETSHRHTTHSD17B10 | |
| SCHEMBL2518861 | 0.67 | SMN1; SMN2 (0.68) | MAPTKDM4ETSHRHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11559538-B2 | Substituted 1,2-oxaborolan-2-ols as PDE4 inhibitors | PFIZER INC. (US) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11559538-B2 | Substituted 1,2-oxaborolan-2-ols as PDE4 inhibitors | PDE4B, PDE4A, PDE3B | MAPT 3874/4885KDM4E 406/4885TSHR 3028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.