Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27863637 | 1.00 | SLC6A2 (0.50) | SLC6A2SLC6A4SMN1; SMN2HPGDLMNA | |
| SCHEMBL31078868 | 0.88 | HPGD (0.55) | SLC6A2SLC6A4SMN1; SMN2HPGDLMNA | |
| SCHEMBL1697616 | 0.88 | HPGD (0.55) | SLC6A2SLC6A4SMN1; SMN2HPGDLMNA | |
| SCHEMBL30196047 | 0.85 | SMN1; SMN2 (0.43) | SLC6A2SLC6A4SMN1; SMN2HPGDLMNA | |
| SCHEMBL2700104 | 0.84 | CHRNB4 (0.51) | SLC6A2SLC6A4SMN1; SMN2HPGDLMNA | |
| SCHEMBL29612256 | 0.83 | CHRNB4 (0.49) | SLC6A2SLC6A4SMN1; SMN2LMNASYK | |
| SCHEMBL63365 | 0.83 | CHRNB4 (0.49) | SLC6A2SLC6A4SMN1; SMN2LMNASYK | |
| SCHEMBL2352417 | 0.81 | HTR1A (0.47) | SLC6A2SLC6A4SMN1; SMN2LMNASYK | |
| Hydrochloric Acid SCHEMBL5669854 | 0.81 | CHRNB4 (0.47) | SLC6A2SLC6A4SMN1; SMN2LMNASYK | |
| SCHEMBL30196232 | 0.81 | MAPT (0.38) | SLC6A2SLC6A4SMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148402-A1 | Boron Containing PDE4 Inhibitors | PFIZER INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-11559538-B2 | Substituted 1,2-oxaborolan-2-ols as PDE4 inhibitors | PFIZER INC. (US) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11559538-B2 | Substituted 1,2-oxaborolan-2-ols as PDE4 inhibitors | PDE4B, PDE4A, PDE3B | SLC6A2 828/4885SLC6A4 940/4885SMN1; SMN2 841/4885 |
| US-20230148402-A1 | Boron Containing PDE4 Inhibitors | PDE4B, PDE4A, PDE3B | SLC6A2 708/4885SLC6A4 472/4885SMN1; SMN2 2176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.