SCHEMBL30197556

SCHEMBL30197556

Brc1cc(Br)c(-c2nc(-c3ccccc3)co2)nc1-c1nc(-c2ccccc2)co1.[Co].[Co]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 5/20 0.47
ENPP1 P22413 4/20 0.47
HSD17B1 P14061 1/20 0.44
HSD17B2 P37059 1/20 0.44
SMO Q99835 2/20 0.39
HSD11B1 P28845 2/20 0.37
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
PIK3R1 P27986 1/20 0.35
PIK3CA P42336 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
ATM Q13315 1/20 0.35
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31231462 1.00 ENPP3 (0.47) ENPP3ENPP1HSD17B1HSD17B2SMO
SCHEMBL30197628 0.81 SMO (0.47) ENPP3ENPP1HSD17B1HSD17B2SMO
SCHEMBL30197618 0.81 ENPP3 (0.47) ENPP3ENPP1HSD17B1HSD17B2SMO
SCHEMBL30197720 0.78 ENPP1 (0.44) ENPP3ENPP1RAB9ANPC1HDAC1
SCHEMBL2198916 0.77 ENPP3 (0.65) ENPP3ENPP1HSD17B1HSD17B2SMO
SCHEMBL278182 0.77 ENPP3 (0.69) ENPP3ENPP1HSD17B1HSD17B2SMO
Benzene SCHEMBL16781371 0.77 ENPP3 (0.69) ENPP3ENPP1HSD17B1HSD17B2SMO
SCHEMBL1200604 0.75 MEN1 (0.58) ENPP3ENPP1HSD17B1HSD17B2SMO
SCHEMBL11566150 0.75 ENPP3 (0.72) ENPP3ENPP1HSD17B1HSD17B2SMO
SCHEMBL31606598 0.75 ENPP3 (0.67) ENPP3ENPP1HSD17B1HSD17B2SMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115836041-A Process for producing optically active compound 住友化学株式会社 2023-03-21 CN disclosed