SCHEMBL30197564

SCHEMBL30197564

Cc1coc(-c2nc(-c3nc(C)co3)c(Br)cc2Br)n1.[Co]

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.32
TACR3 P29371 1/20 0.31
TGFBR1 P36897 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30197626 0.80 CCR4 (0.31)
SCHEMBL30197884 0.77 PDE4B (0.32) PDE4BTACR3TGFBR1
SCHEMBL30197714 0.77 PDE4B (0.32) PDE4BTACR3TGFBR1
SCHEMBL30197550 0.77
SCHEMBL30198031 0.77 PDE4B (0.35) PDE4B
SCHEMBL21083458 0.72 HDAC1 (0.54) TGFBR1TSHR
SCHEMBL21598699 0.69 SMN1; SMN2 (0.35)
SCHEMBL6639205 0.67 HDAC1 (0.51) PDE4BTSHR
SCHEMBL2228307 0.66 ENPP3 (0.39) PDE4BTGFBR1TSHR
SCHEMBL1200783 0.65 CCR1 (0.44) PDE4BTACR3TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115836041-B Process for producing optically active compound 住友化学株式会社 2024-09-17 CN disclosed
CN-115836041-A Process for producing optically active compound 住友化学株式会社 2023-03-21 CN disclosed