Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 13/20 | 0.56 |
| ▸ | PARP11 | Q9NR21 | 11/20 | 0.56 |
| ▸ | PARP1 | P09874 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23952300 | 1.00 | PARP10 (0.56) | PARP10PARP11PARP1ALDH1A1ALDH2 | |
| SCHEMBL30197872 | 0.79 | PARP10 (0.56) | PARP10PARP11PARP1ACHERAF1 | |
| SCHEMBL24886285 | 0.79 | PARP10 (0.56) | PARP10PARP11PARP1ACHERAF1 | |
| SCHEMBL29698189 | 0.79 | PARP10 (0.56) | PARP10PARP11PARP1ACHERAF1 | |
| SCHEMBL23951998 | 0.79 | PARP10 (0.56) | PARP10PARP11PARP1ACHERAF1 | |
| SCHEMBL22982047 | 0.79 | PARP10 (0.56) | PARP10PARP11PARP1ACHERAF1 | |
| SCHEMBL22990298 | 0.79 | PARP10 (0.56) | PARP10PARP11PARP1KDM4EACHE | |
| SCHEMBL29698302 | 0.79 | PARP10 (0.56) | PARP10PARP11PARP1KDM4EACHE | |
| SCHEMBL22990374 | 0.76 | PARP10 (0.51) | PARP10PARP11PARP1KDM4EACHE | |
| SCHEMBL22981764 | 0.76 | PARP10 (0.51) | PARP10PARP11PARP1ACHERAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397412-B | Modulators of MAS-related G protein receptor X4 and related products and methods | 伊赛恩特制药公司 | 2025-03-25 | — | — | CN | disclosed |
| EP-4135691-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-02-22 | — | — | EP | disclosed |
| CN-115397412-A | Modulators of MAS-related G protein receptor X4 and related products and methods | 伊赛恩特制药公司 | 2022-11-25 | — | — | CN | disclosed |