SCHEMBL30197743

SCHEMBL30197743

CCN(CC)CCCCNc1ncc2cc(-c3cc(C)cc(C)c3)c(NC(=O)NC(C)(C)C)nc2n1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 20/20 0.81
FGFR2 P21802 10/20 0.81
FGFR4 P22455 10/20 0.81
FGFR3 P22607 10/20 0.81
KDR P35968 8/20 0.81
FLT1 P17948 7/20 0.81
FLT4 P35916 7/20 0.81
SRC P12931 4/20 0.81
GLA P06280 1/20 0.81
CSK P41240 1/20 0.81
KMT2A Q03164 1/20 0.81
ATM Q13315 1/20 0.81
EGFR P00533 4/20 0.73
PRKD3 O94806 1/20 0.73
PRKCG P05129 1/20 0.73
PRKCB P05771 1/20 0.73
PRKCA P17252 1/20 0.73
PRKCH P24723 1/20 0.73
PRKCI P41743 1/20 0.73
PRKCE Q02156 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16489372 0.93 FGFR1 (0.91) FGFR1FGFR2FGFR4FGFR3KDR
SCHEMBL19338028 0.91 FGFR1 (0.79) FGFR1FGFR2FGFR4FGFR3KDR
Pd-173074 SCHEMBL177946 0.89 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3KDR
Pd-173074 SCHEMBL29828472 0.89 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3KDR
SCHEMBL22144559 0.87 FGFR1 (0.95) FGFR1FGFR2FGFR4FGFR3KDR
SCHEMBL17814860 0.86 FGFR1 (0.90) FGFR1FGFR2FGFR4FGFR3KDR
SCHEMBL15624527 0.85 FGFR1 (0.87) FGFR1FGFR2FGFR4FGFR3KDR
SCHEMBL30368635 0.84 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3KDR
SCHEMBL29375761 0.84 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3KDR
SCHEMBL4301366 0.84 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277135-A1 METHOD FOR PRODUCING CELLS CONSTITUTING NASAL EPITHELIUM, AND CELL POPULATION INCLUDING CELLS CONSTITUTING NASAL EPITHELIUM OR PROGENITOR CELLS THEREOF 住友化学株式会社 2023-01-05 WO disclosed