SCHEMBL3019812

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3019811	1.00	LRRK2 (0.36)	LRRK2CSF1RHSD11B1TDO2ENPP2
	SCHEMBL1277591	0.89	TTK (0.33)	LRRK2CSF1RHSD11B1ENPP2CNR2
	SCHEMBL1277587	0.89	TTK (0.33)	LRRK2CSF1RHSD11B1ENPP2CNR2
	SCHEMBL3029306	0.89	CSF1R (0.33)	CSF1RTDO2CCNKCDK9CNR2
	SCHEMBL3029304	0.89	CSF1R (0.33)	CSF1RTDO2CCNKCDK9CNR2
	SCHEMBL3024062	0.88	RIPK1 (0.35)	LRRK2NPY5RCNR2CYP3A4IRAK4
	SCHEMBL3024058	0.88	RIPK1 (0.35)	LRRK2NPY5RCNR2CYP3A4IRAK4
	SCHEMBL3032060	0.87	CCNK (0.33)	LRRK2CSF1RTDO2CCNKCDK9
	SCHEMBL3032057	0.87	CCNK (0.33)	LRRK2CSF1RTDO2CCNKCDK9
	SCHEMBL1277673	0.87	TTK (0.36)	LRRK2HSD11B1ENPP2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.