Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
| ▸ | GLP1R | P43220 | 6/20 | 0.48 |
| ▸ | GIPR | P48546 | 6/20 | 0.48 |
| ▸ | NPY2R | P49146 | 7/20 | 0.47 |
| ▸ | NPY4R | P50391 | 7/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.47 |
| ▸ | NPY1R | P25929 | 5/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29453248 | 1.00 | BACE1 (0.51) | BACE1CTSDAPLNRGLP1RGIPR | |
| SCHEMBL30414165 | 0.88 | NTSR1 (0.49) | BACE1CTSDNPY2RNPY4RNPY5R | |
| SCHEMBL30974359 | 0.87 | BACE1 (0.53) | BACE1CTSDNPY2RNPY4RNPY5R | |
| SCHEMBL29855903 | 0.86 | NPY2R (0.53) | APLNRGLP1RGIPRNPY2RNPY4R | |
| SCHEMBL30400667 | 0.85 | CALCRL (0.49) | BACE1CTSDNPY2RNPY4RNPY5R | |
| SCHEMBL30401223 | 0.85 | CALCRL (0.49) | BACE1CTSDNPY2RNPY4RNPY5R | |
| SCHEMBL30401358 | 0.85 | CALCRL (0.50) | BACE1CTSDNPY2RNPY4RNPY5R | |
| SCHEMBL30400966 | 0.85 | CALCRL (0.50) | BACE1CTSDNPY2RNPY4RNPY5R | |
| SCHEMBL30399534 | 0.85 | CALCRL (0.50) | BACE1CTSDNPY2RNPY4RNPY5R | |
| SCHEMBL30400261 | 0.84 | CALCRL (0.49) | BACE1CTSDNPY2RNPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117224655-B | Application of scorpion venom heat-resistant synthetic peptide (SVHRSP) in preparation of medicine for treating intestinal inflammation | 大连医科大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-114028537-B | Pharmaceutical composition containing SVHRSP scorpion venom peptide and preparation method thereof | 上海万锦医药科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117224655-A | Application of scorpion venom heat-resistant synthetic peptide (SVHRSP) in preparation of medicines for treating intestinal inflammation | 大连医科大学 | 2023-12-15 | — | — | CN | disclosed |
| EP-3505530-B1 | SCORPION VENOM HEAT-RESISTANT SYNTHESIZED PEPTIDE AND USES THEREOF | WANJIN PHARMACEUTICALS TECH SHANGHAI CO LTD (CN) | 2023-02-22 | — | — | EP | disclosed |