SCHEMBL30198507

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)CNC(=O)CNC(=O)[C@@H](N)CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O)[C@@H](C)O)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	7/20	0.48

▸	NPY4R	P50391	7/20	0.48

▸	NPY5R	Q15761	7/20	0.48

▸	NPY1R	P25929	5/20	0.48

▸	CALCR	P30988	7/20	0.47

▸	RAMP3	O60896	3/20	0.47

▸	EP300	Q09472	1/20	0.47

▸	HIF1A	Q16665	1/20	0.47

▸	KEAP1	Q14145	1/20	0.47

▸	CAPN1	P07384	2/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31461965	0.88	EP300 (0.46)	CALCRRAMP3EP300HIF1ACAPN1
SCHEMBL30524360	0.86	F2 (0.53)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30997383	0.86	RAMP3 (0.50)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30432575	0.86	CALCR (0.51)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL31462127	0.86	EP300 (0.48)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30930172	0.86	NPY2R (0.52)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30067104	0.85	PTPN1 (0.48)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL31461906	0.85	F2 (0.47)	CALCRRAMP3EP300HIF1A
SCHEMBL30930162	0.84	RAMP3 (0.50)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL31462082	0.84	OPRD1 (0.54)	EP300HIF1AKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-115835887-A	Gene therapy compositions and methods for treating parkinson's disease	牛津生物医学（英国）有限公司	2023-03-21	—	—	CN	disclosed