Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.53 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.53 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.48 |
| ▸ | RELA | Q04206 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29569445 | 0.91 | MAPT (0.62) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL28140891 | 0.84 | MAPT (0.51) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL28812854 | 0.83 | BCHE (0.60) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL9240254 | 0.83 | MAPT (0.57) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL9240252 | 0.83 | MAPT (0.57) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL17541840 | 0.83 | MAPT (0.61) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL17541845 | 0.83 | MAPT (0.61) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL9664021 | 0.82 | MAPT (0.60) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL27969001 | 0.82 | MAPT (0.60) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL9006476 | 0.82 | MAPT (0.69) | MAPTRAB9ANPC1LMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11565235-B2 | System and method for removing contaminants | YOUNGSTOWN STATE UNIVERSITY (US) | 2023-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11565235-B2 | System and method for removing contaminants | RIF1, ATF1, MUS81 | MAPT 1858/4885RAB9A 4377/4885NPC1 2650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.