SCHEMBL9006476

SCHEMBL9006476

O=C(C=Cc1ccccc1C=CC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.69
MAOB P27338 3/20 0.69
BCHE P06276 3/20 0.69
LMNA P02545 2/20 0.69
PLIN1 O60240 1/20 0.69
TNFRSF1A P19438 1/20 0.69
ACHE P22303 1/20 0.69
RECQL P46063 1/20 0.69
PLIN5 Q00G26 1/20 0.69
CYP1B1 Q16678 1/20 0.69
ABHD5 Q8WTS1 1/20 0.69
RAB9A P51151 7/20 0.68
NPC1 O15118 5/20 0.68
TYR P14679 1/20 0.62
KMT2A Q03164 4/20 0.60
NFKB1 P19838 3/20 0.60
NFKB2 Q00653 3/20 0.60
RELA Q04206 3/20 0.60
CYP3A4 P08684 2/20 0.60
HSPD1 P10809 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31549898 0.92 MAPT (0.60) MAPTMAOBBCHELMNAPLIN1
SCHEMBL4120849 0.90 MAPT (0.58) MAPTMAOBBCHELMNAPLIN1
SCHEMBL28301997 0.90 MAPT (0.58) MAPTMAOBBCHELMNAPLIN1
SCHEMBL4120846 0.90 MAPT (0.58) MAPTMAOBBCHELMNAPLIN1
SCHEMBL3258196 0.90 MAPT (0.58) MAPTMAOBBCHELMNAPLIN1
SCHEMBL29569445 0.90 MAPT (0.62) MAPTMAOBBCHELMNAPLIN1
SCHEMBL626787 0.88 MAPT (0.75) MAPTMAOBBCHELMNAPLIN1
SCHEMBL10893208 0.88 MAPT (0.75) MAPTMAOBBCHELMNAPLIN1
SCHEMBL29420130 0.88 MAPT (0.75) MAPTMAOBBCHELMNAPLIN1
SCHEMBL626785 0.88 MAPT (0.75) MAPTMAOBBCHELMNAPLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US claimed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP claimed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US claimed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO claimed
JP-1056643-A None JP disclosed
JP-S6456643-A ADDITION REACTION TYPE COMPOUND, PRODUCTION AND RELATED SUBSTANCE THEREOF HITACHI LTD 1989-03-03 JP disclosed