Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199385 | 0.89 | HTR2C (0.51) | HTR2CSMN1; SMN2NPC1RAB9APDK1 | |
| SCHEMBL30199651 | 0.86 | HTR2C (0.53) | HTR2CSMN1; SMN2NPC1RAB9APDK1 | |
| SCHEMBL3662621 | 0.83 | HTR2C (0.58) | HTR2CSMN1; SMN2NPC1RAB9APDK1 | |
| SCHEMBL31393228 | 0.83 | HTR2C (0.58) | HTR2CSMN1; SMN2NPC1RAB9APDK1 | |
| SCHEMBL31679608 | 0.83 | HTR2C (0.46) | HTR2CSMN1; SMN2NPC1RAB9APDK1 | |
| SCHEMBL30199761 | 0.83 | HTR2C (0.46) | HTR2CSMN1; SMN2NPC1RAB9APDK1 | |
| SCHEMBL14372548 | 0.79 | SMN1; SMN2 (0.60) | HTR2CSMN1; SMN2NPC1RAB9APDK1 | |
| SCHEMBL16472423 | 0.79 | SMN1; SMN2 (0.60) | HTR2CSMN1; SMN2NPC1RAB9APDK1 | |
| SCHEMBL15218647 | 0.79 | SMN1; SMN2 (0.60) | HTR2CSMN1; SMN2NPC1RAB9APDK1 | |
| SCHEMBL29849418 | 0.77 | CHRM1 (0.60) | HTR2CSMN1; SMN2NPC1RAB9APDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4171567-B1 | CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | CELGENE CORP (US) | 2025-09-03 | — | — | EP | disclosed |
| CN-115968293-A | Cereblon binding compounds, compositions thereof, and methods of use thereof for treatment | 新基公司 | 2023-04-14 | — | — | CN | disclosed |
| US-11560371-B2 | Cereblon binding compounds, compositions thereof, and methods of treatment therewith | CELGENE CORPORATION (US) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560371-B2 | Cereblon binding compounds, compositions thereof, and methods of treatment therewith | CRBN, AR, SHBG | HTR2C 946/4885SMN1; SMN2 734/4885NPC1 1516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.