Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 6/20 | 0.56 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098117 | 1.00 | SYK (0.56) | SYKCD274HRH3KDM4EALDH1A1 | |
| SCHEMBL29098064 | 0.85 | HRH3 (0.46) | SYKCD274HRH3ADRA2AADRA2B | |
| SCHEMBL30199461 | 0.85 | HRH3 (0.46) | SYKCD274HRH3ADRA2AADRA2B | |
| SCHEMBL17712567 | 0.82 | NPC1 (0.55) | HRH3KDM4EALDH1A1SMN1; SMN2MAOA | |
| SCHEMBL15897864 | 0.81 | MAOA (0.47) | SYKHRH3KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3503754 | 0.81 | HRH3 (0.59) | CD274HRH3PNMTMAOAMAOB | |
| SCHEMBL29474892 | 0.81 | HRH3 (0.59) | CD274HRH3PNMTMAOAMAOB | |
| Hydrochloric Acid SCHEMBL29052776 | 0.80 | HRH3 (0.58) | CD274HRH3PNMTMAOAMAOB | |
| Hydrochloric Acid SCHEMBL30515385 | 0.80 | HRH3 (0.58) | CD274HRH3PNMTMAOAMAOB | |
| SCHEMBL23537837 | 0.80 | HRH3 (0.46) | SYKCD274HRH3ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-B | Parallel ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |