Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 7/20 | 0.72 |
| ▸ | CD44 | P16070 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2750868 | 1.00 | PNMT (0.72) | PNMTCD44MAOBHTR2CADRA2A | |
| Hydrochloric Acid SCHEMBL1124563 | 0.98 | PNMT (0.70) | PNMTCD44MAOBHTR2CADRA2A | |
| SCHEMBL11325485 | 0.89 | PNMT (0.62) | PNMTCD44MAOBHTR2CADRA2A | |
| SCHEMBL10879871 | 0.86 | PNMT (0.75) | PNMTCD44HTR2CADRA2AADRA2B | |
| SCHEMBL1852509 | 0.84 | PNMT (1.00) | PNMTCD44MAOBHTR2CADRA2A | |
| Ammonia Solution, Strong SCHEMBL20358513 | 0.82 | PNMT (0.96) | PNMTCD44MAOBHTR2CADRA2A | |
| Hydrochloric Acid SCHEMBL1124149 | 0.82 | PNMT (0.96) | PNMTCD44MAOBHTR2CADRA2A | |
| SCHEMBL3171440 | 0.81 | PNMT (0.68) | PNMTCD44MAOBHTR2CADRA2A | |
| SCHEMBL31158975 | 0.81 | PNMT (0.68) | PNMTCD44MAOBHTR2CADRA2A | |
| Hydrochloric Acid SCHEMBL1636223 | 0.79 | PNMT (0.66) | PNMTCD44MAOBHTR2CADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427409-B | Pyrimidine-4 (3H) -one derivatives as TRPV4 antagonists | 拉夸里亚创药株式会社 | 2025-02-25 | — | — | CN | disclosed |
| CN-115594669-B | Parallel ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| WO-2024201248-A1 | COMPOUNDS AND METHODS FOR DEGRADING GSPT1 | PIN THERAPEUTICS, INC. (KR) | 2024-10-03 | — | — | WO | disclosed |
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |