Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.61 |
| ▸ | GHSR | Q92847 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199596 | 0.88 | NR1H2 (0.63) | NR1H2ESR2GHSRABHD6ESR1 | |
| SCHEMBL29388008 | 0.88 | NR1H2 (0.72) | NR1H2ESR2MEN1KMT2ASTS | |
| SCHEMBL25430802 | 0.86 | NR1H2 (0.61) | NR1H2ESR2GHSRSTSABHD6 | |
| SCHEMBL30519086 | 0.86 | NR1H2 (0.61) | NR1H2ESR2GHSRSTSABHD6 | |
| SCHEMBL29097838 | 0.86 | ESR2 (0.58) | NR1H2ESR2GHSRMAPK1MAPT | |
| SCHEMBL30199070 | 0.86 | ESR2 (0.58) | NR1H2ESR2GHSRMAPK1MAPT | |
| SCHEMBL8107263 | 0.85 | ESR2 (0.64) | NR1H2ESR2GHSRSTSLMNA | |
| SCHEMBL30390692 | 0.84 | NR1H2 (0.70) | NR1H2ESR2STSABHD6ESR1 | |
| SCHEMBL6438594 | 0.84 | NR1H2 (0.70) | NR1H2ESR2STSABHD6ESR1 | |
| SCHEMBL13285564 | 0.84 | NR1H2 (0.70) | NR1H2ESR2GHSRABHD6ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-B | Parallel ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |