Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.64 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199574 | 0.85 | NR1H2 (0.63) | ESR2NR1H2ABHD6ESR1STS | |
| SCHEMBL19684692 | 0.85 | ESR2 (0.78) | ESR2NR1H2ABHD6ESR1STS | |
| SCHEMBL31621670 | 0.85 | ESR2 (0.78) | ESR2NR1H2ABHD6ESR1STS | |
| SCHEMBL13285564 | 0.83 | NR1H2 (0.70) | ESR2NR1H2ABHD6ESR1MAPK1 | |
| SCHEMBL4917789 | 0.82 | ESR2 (0.55) | ESR2NR1H2GHSRNPC1RAB9A | |
| SCHEMBL3694640 | 0.81 | ESR2 (0.62) | ESR2NR1H2ABHD6ESR1MAPK1 | |
| SCHEMBL29368645 | 0.81 | ESR2 (0.72) | ESR2NR1H2ABHD6ESR1STS | |
| SCHEMBL15755296 | 0.81 | ESR2 (0.72) | ESR2NR1H2ABHD6ESR1STS | |
| SCHEMBL31317916 | 0.81 | ESR2 (0.55) | ESR2NR1H2GHSRHDAC8 | |
| SCHEMBL29097945 | 0.81 | ESR2 (0.55) | ESR2NR1H2GHSRHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141227-A1 | NOVEL PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2008-11-20 | — | — | WO | disclosed |