Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | RXRG | P48443 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29097987 | 1.00 | MAOB (0.52) | MAOBMAOAHRH3CD274NPC1 | |
| SCHEMBL29097902 | 0.86 | PNMT (0.58) | MAOBMAOAHRH3CD274NPC1 | |
| SCHEMBL30199477 | 0.86 | PNMT (0.58) | MAOBMAOAHRH3NPC1RAB9A | |
| SCHEMBL30199270 | 0.86 | MAOB (0.52) | MAOBMAOAHRH3ADRA2AADRA2B | |
| SCHEMBL30199572 | 0.86 | PNMT (0.58) | MAOBMAOAHRH3CD274NPC1 | |
| SCHEMBL3876596 | 0.86 | PNMT (0.58) | MAOBMAOAHRH3NPC1RAB9A | |
| SCHEMBL29097941 | 0.86 | MAOB (0.52) | MAOBMAOAHRH3ADRA2AADRA2B | |
| SCHEMBL29474892 | 0.86 | HRH3 (0.59) | MAOBMAOAHRH3CD274 | |
| SCHEMBL3503754 | 0.86 | HRH3 (0.59) | MAOBMAOAHRH3CD274 | |
| Hydrochloric Acid SCHEMBL4808095 | 0.85 | PNMT (0.56) | MAOBMAOAHRH3ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-B | Parallel ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |