Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.30 |
| ▸ | JAK3 | P52333 | 2/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26389026 | 0.84 | AR (0.41) | ARFFAR1PDK2 | |
| SCHEMBL12017377 | 0.84 | AR (0.41) | ARFFAR1PDK2 | |
| SCHEMBL15518451 | 0.84 | FFAR1 (0.37) | ARFFAR1 | |
| SCHEMBL1819606 | 0.84 | FFAR1 (0.55) | ARFFAR1PDK2JAK1JAK3 | |
| SCHEMBL1845692 | 0.81 | FFAR1 (0.36) | ARFFAR1 | |
| SCHEMBL9275281 | 0.81 | FFAR1 (0.39) | ARFFAR1JAK1JAK3JAK2 | |
| SCHEMBL23022274 | 0.80 | AR (0.41) | ARFFAR1 | |
| SCHEMBL16876130 | 0.80 | FFAR1 (0.41) | ARFFAR1ADORA2AJAK1JAK3 | |
| SCHEMBL16876129 | 0.80 | FFAR1 (0.41) | ARFFAR1ADORA2AJAK1JAK3 | |
| SCHEMBL2378629 | 0.79 | AR (0.38) | ARFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4401729-A1 | BCL-XL DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-07-24 | — | — | EP | disclosed |
| WO-2023044046-A1 | BCL-XL DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-03-23 | — | — | WO | disclosed |