SCHEMBL15518451

SCHEMBL15518451

CC(C)(N)Cn1cc(I)cn1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.37
AR P10275 1/20 0.36
ALOX5AP P20292 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30200569 0.84 AR (0.40) FFAR1AR
SCHEMBL12017377 0.81 AR (0.41) FFAR1AR
SCHEMBL1819606 0.81 FFAR1 (0.55) FFAR1ARALOX5AP
SCHEMBL26389026 0.81 AR (0.41) FFAR1AR
SCHEMBL23762952 0.78 NOS1 (0.37) FFAR1ARALOX5AP
SCHEMBL9275281 0.78 FFAR1 (0.39) FFAR1AR
SCHEMBL1845692 0.78 FFAR1 (0.36) FFAR1AR
SCHEMBL16876129 0.77 FFAR1 (0.41) FFAR1AR
SCHEMBL23022274 0.77 AR (0.41) FFAR1ARALOX5AP
SCHEMBL16876130 0.77 FFAR1 (0.41) FFAR1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2892889-A1 INHIBITOR COMPOUNDS Cancer Research Technology Ltd (GB) 2015-07-15 EP disclosed
WO-2014037750-A1 INHIBITOR COMPOUNDS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2014-03-13 WO disclosed