Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30201150 | 0.85 | UCHL1 (0.41) | UCHL1FFAR1 | |
| SCHEMBL18125399 | 0.84 | UCHL1 (0.45) | UCHL1FFAR1LPLLIPG | |
| SCHEMBL1358786 | 0.80 | UCHL1 (0.41) | UCHL1FFAR1 | |
| SCHEMBL25428252 | 0.80 | UCHL1 (0.43) | UCHL1FFAR1 | |
| SCHEMBL21266884 | 0.78 | UCHL1 (0.43) | UCHL1FFAR1 | |
| SCHEMBL30200601 | 0.78 | FFAR1 (0.43) | UCHL1FFAR1 | |
| SCHEMBL30508697 | 0.77 | UCHL1 (0.40) | UCHL1FFAR1 | |
| SCHEMBL21266730 | 0.76 | UCHL1 (0.38) | UCHL1FFAR1 | |
| SCHEMBL24896720 | 0.75 | UCHL1 (0.44) | UCHL1FFAR1 | |
| SCHEMBL25428501 | 0.75 | UCHL1 (0.39) | UCHL1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4401729-A1 | BCL-XL DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-07-24 | — | — | EP | disclosed |
| WO-2023044046-A1 | BCL-XL DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-03-23 | — | — | WO | disclosed |