Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.68 |
| ▸ | DRD3 | P35462 | 7/20 | 0.68 |
| ▸ | DRD4 | P21917 | 3/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.68 |
| ▸ | DRD1 | P21728 | 1/20 | 0.68 |
| ▸ | DRD5 | P21918 | 1/20 | 0.68 |
| ▸ | HTR7 | P34969 | 1/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28966833 | 1.00 | DRD2 (0.68) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL339581 | 0.84 | CHRM3 (0.77) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL3312525 | 0.84 | CHRM3 (0.77) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL3313069 | 0.84 | CHRM3 (0.77) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL3315993 | 0.83 | DRD2 (0.62) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL338954 | 0.83 | DRD2 (0.62) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL7328268 | 0.82 | DRD2 (0.50) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL21262950 | 0.82 | DRD2 (0.90) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL21083262 | 0.82 | DRD2 (0.90) | DRD2DRD3DRD4HTR1ADRD1 | |
| 5-Oh-Dpat SCHEMBL279021 | 0.81 | DRD2 (1.00) | DRD2DRD3DRD4HTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611708-B | Preparation method of rotigotine impurity K | 北京福元医药股份有限公司沧州分公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-115611708-A | Preparation method of rotigotine impurity K | 北京福元医药股份有限公司沧州分公司 | 2023-01-17 | — | — | CN | disclosed |