SCHEMBL30201400

SCHEMBL30201400

O=C(NC1C[C@H]2CC[C@@H](C1)N2Cc1nccs1)c1ccc2cc[nH]c2c1

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMYD3 Q9H7B4 1/20 0.48
CYP2D6 P10635 1/20 0.46
CCR3 P51677 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30201245 0.86 MAPK11 (0.48) SMYD3
SCHEMBL24950984 0.83 MAPT (0.58) SMYD3CYP2D6
SCHEMBL30201525 0.83 MAPT (0.58) SMYD3CYP2D6
SCHEMBL30201472 0.83 MEN1 (0.52) SMYD3
SCHEMBL30201432 0.82 DRD4 (0.55) SMYD3
SCHEMBL30201471 0.82 SMYD3 (0.48) SMYD3
SCHEMBL24950982 0.82 SMYD3 (0.48) SMYD3
SCHEMBL30201410 0.82 SMYD3 (0.48) SMYD3
SCHEMBL30201438 0.81 SMYD3 (0.48) SMYD3
SCHEMBL30201445 0.81 SMYD3 (0.48) SMYD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4376818-B1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS ZOETIS SERVICES LLC (US) 2025-06-18 EP claimed
WO-2023009330-A1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS ZOETIS SERVICES LLC (US) 2023-02-02 WO claimed
CN-117729914-A Serotonin 5-HT2B inhibiting compounds 硕腾服务有限责任公司 2024-03-19 CN disclosed
WO-2023009330-A1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS ZOETIS SERVICES LLC (US) 2023-02-02 WO disclosed