SCHEMBL30201525

SCHEMBL30201525

O=C(NC1C[C@H]2CC[C@@H](C1)N2Cc1cccs1)c1ccc2cc[nH]c2c1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.58
MEN1 O00255 1/20 0.52
LMNA P02545 1/20 0.52
KMT2A Q03164 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
SMYD3 Q9H7B4 1/20 0.52
CYP2D6 P10635 2/20 0.51
CYP2C19 P33261 1/20 0.51
ALDH1A1 P00352 1/20 0.50
CYP2C9 P11712 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24950984 1.00 MAPT (0.58) MAPTMEN1LMNAKMT2ASMN1; SMN2
SCHEMBL30201364 0.84 MEN1 (0.64) MEN1KMT2A
SCHEMBL30201410 0.84 SMYD3 (0.48) SMYD3
SCHEMBL30201400 0.83 SMYD3 (0.48) SMYD3CYP2D6
SCHEMBL30201472 0.82 MEN1 (0.52) MEN1KMT2ASMYD3
SCHEMBL30201471 0.82 SMYD3 (0.48) SMYD3
SCHEMBL24950982 0.82 SMYD3 (0.48) SMYD3
SCHEMBL30201412 0.81 CXCR6 (0.55) MEN1KMT2ASMYD3
SCHEMBL30201517 0.81 SMYD3 (0.52) SMYD3
SCHEMBL30201378 0.80 OPRK1 (0.61) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4376818-B1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS ZOETIS SERVICES LLC (US) 2025-06-18 EP claimed
CN-117729914-A Serotonin 5-HT2B inhibiting compounds 硕腾服务有限责任公司 2024-03-19 CN claimed
WO-2023009330-A1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS ZOETIS SERVICES LLC (US) 2023-02-02 WO claimed
CN-117729914-A Serotonin 5-HT2B inhibiting compounds 硕腾服务有限责任公司 2024-03-19 CN disclosed
WO-2023009330-A1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS ZOETIS SERVICES LLC (US) 2023-02-02 WO disclosed