Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.65 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.46 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.46 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.46 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.46 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.46 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.46 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.46 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.46 |
| ▸ | CACNA2D4 | Q7Z3S7 | 2/20 | 0.46 |
| ▸ | CACNA2D3 | Q8IZS8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12283499 | 0.95 | GPR119 (0.72) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL14634692 | 0.95 | GPR119 (0.72) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL2776764 | 0.91 | GPR119 (0.69) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL29749146 | 0.86 | GPR119 (0.66) | GPR119NPBWR1MCHR1 | |
| SCHEMBL20137646 | 0.86 | GPR119 (0.66) | GPR119NPBWR1MCHR1 | |
| SCHEMBL5266887 | 0.85 | GPR119 (0.65) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL17654170 | 0.85 | GPR119 (0.65) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL2776282 | 0.84 | GPR119 (0.64) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL3343917 | 0.84 | GPR119 (0.64) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL29686112 | 0.84 | GPR119 (0.60) | GPR119PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12258328-B2 | 6-membered heteroaryl-containing aminopyridine compounds as EGFR inhibitors | YUHAN CORPORATION (KR) | 2025-03-25 | — | — | US | disclosed |
| US-20230090406-A1 | 6-MEMBERED HETEROARYL-CONTAINING AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | YUHAN CORPORATION (KR) | 2023-03-23 | — | — | US | disclosed |
| WO-2023027517-A1 | 6-MEMBERED HETEROARYL-CONTAINING AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | YUHAN CORPORATION (KR) | 2023-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230090406-A1 | 6-MEMBERED HETEROARYL-CONTAINING AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | EGFR, ERBB2, ERBB4 | GPR119 2593/4885CACNB4 3272/4885CACNA1A 3813/4885 |
| US-12258328-B2 | 6-membered heteroaryl-containing aminopyridine compounds as EGFR inhibitors | EGFR, ERBB2, ERBB4 | GPR119 2593/4885CACNB4 3272/4885CACNA1A 3813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.