Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 10/20 | 0.60 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.60 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25074070 | 1.00 | DDB1 (0.60) | DDB1CRBNGPR119 | |
| SCHEMBL29223447 | 0.87 | CRBN (0.62) | DDB1CRBNGPR119 | |
| SCHEMBL30201796 | 0.85 | DDB1 (0.67) | DDB1CRBNGPR119 | |
| SCHEMBL25143681 | 0.85 | DDB1 (0.67) | DDB1CRBNGPR119 | |
| SCHEMBL25221368 | 0.84 | DDB1 (0.72) | DDB1CRBNGPR119 | |
| SCHEMBL30442191 | 0.84 | DDB1 (0.72) | DDB1CRBNGPR119 | |
| SCHEMBL24881041 | 0.83 | CRBN (0.70) | DDB1CRBNGPR119 | |
| SCHEMBL29977355 | 0.83 | CRBN (0.70) | DDB1CRBNGPR119 | |
| SCHEMBL25074522 | 0.83 | CRBN (0.70) | DDB1CRBNGPR119 | |
| SCHEMBL30201627 | 0.83 | CRBN (0.70) | DDB1CRBNGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4512402-A2 | BIFUNCTIONAL DEGRADERS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES AND THERAPEUTIC USE THEREOF | Nurix Therapeutics, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| EP-4367118-A1 | BIFUNCTIONAL DEGRADERS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES AND THERAPEUTIC USE THEREOF | Nurix Therapeutics, Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023023255-A1 | BIFUNCTIONAL DEGRADERS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES AND THERAPEUTIC USE THEREOF | NURIX THERAPEUTICS, INC. (US) | 2023-02-23 | — | — | WO | disclosed |