Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3560112 | 0.91 | UTS2R (0.41) | MAPTUTS2RSMN1; SMN2CNR1LMNA | |
| SCHEMBL3937222 | 0.91 | DRD2 (0.45) | MAPTNAMPTUTS2RSMN1; SMN2CNR1 | |
| SCHEMBL3564763 | 0.86 | NAMPT (0.47) | MAPTNAMPTUTS2RMEN1KMT2A | |
| SCHEMBL3941457 | 0.86 | CNR1 (0.39) | MAPTNAMPTUTS2RSMN1; SMN2CNR1 | |
| SCHEMBL3556658 | 0.84 | KMT2A (0.44) | MAPTNAMPTUTS2RMEN1KMT2A | |
| SCHEMBL3561750 | 0.84 | NAMPT (0.49) | NAMPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL3566882 | 0.84 | CCR3 (0.42) | MAPTNAMPTMEN1KMT2ACCR3 | |
| SCHEMBL3562346 | 0.84 | NAMPT (0.43) | NAMPTALDH1A1MEN1KMT2ACCR3 | |
| SCHEMBL3562290 | 0.83 | CA1 (0.49) | MAPTNAMPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3562413 | 0.83 | KMT2A (0.42) | MAPTNAMPTUTS2RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4851328-B2 | — | — | 2012-01-11 | — | — | JP | claimed |
| EP-1670470-B1 | PYRIDINE DERIVATIVES AND USE THEREOF AS UROTENSIN II ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2009-04-08 | — | — | EP | claimed |