Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 14/20 | 0.51 |
| ▸ | PPARA | Q07869 | 14/20 | 0.51 |
| ▸ | PPARG | P37231 | 11/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13499289 | 0.87 | PPARD (0.46) | PPARDPPARAPPARGHSD17B3ALDH1A1 | |
| SCHEMBL16196902 | 0.83 | PPARD (0.48) | PPARDPPARAPPARGHSD17B3ALDH1A1 | |
| SCHEMBL30203042 | 0.83 | ALDH1A1 (0.65) | PPARDPPARAPPARGHSD17B3ALDH1A1 | |
| SCHEMBL5717743 | 0.81 | PPARD (0.47) | PPARDPPARAPPARGHSD17B3ALDH1A1 | |
| SCHEMBL16196818 | 0.80 | PPARD (0.48) | PPARDPPARAPPARGHSD17B3ROCK2 | |
| SCHEMBL28479387 | 0.78 | PPARD (0.43) | PPARDPPARAPPARGHSD17B3ROCK2 | |
| SCHEMBL16196788 | 0.77 | PPARD (0.47) | PPARDPPARAPPARGHSD17B3ALDH1A1 | |
| SCHEMBL20639871 | 0.76 | MAPT (0.49) | PPARDPPARAPPARGHSD17B3ALDH1A1 | |
| SCHEMBL30203112 | 0.76 | PPARD (0.36) | PPARDPPARAPPARGHSD17B3ALDH1A1 | |
| SCHEMBL21382200 | 0.76 | PPARD (0.41) | PPARDPPARAPPARGHSD17B3ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023024425-A1 | TRIAZOLONE COMPOUND AND MEDICINAL USE THEREOF | 中国药科大学 | 2023-03-02 | — | — | WO | disclosed |