Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28954901 | 1.00 | L3MBTL1 (0.59) | L3MBTL1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL28954836 | 0.89 | L3MBTL1 (0.56) | L3MBTL1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL30205182 | 0.89 | L3MBTL1 (0.56) | L3MBTL1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL28954772 | 0.89 | L3MBTL1 (0.58) | L3MBTL1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL30205165 | 0.89 | L3MBTL1 (0.58) | L3MBTL1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL30205327 | 0.84 | L3MBTL1 (0.53) | L3MBTL1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL28954804 | 0.84 | L3MBTL1 (0.53) | L3MBTL1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL30205256 | 0.84 | MYD88 (0.62) | L3MBTL1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL28954884 | 0.84 | MYD88 (0.62) | L3MBTL1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL28954798 | 0.82 | L3MBTL1 (0.51) | L3MBTL1LMNAMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710251-B | Medullary differentiation factor 88 inhibitor and preparation method and application thereof | 杭州医学院 | 2024-05-28 | — | — | CN | claimed |
| CN-115710251-A | Myeloid differentiation factor 88 inhibitor and preparation method and application thereof | 杭州医学院 | 2023-02-24 | — | — | CN | claimed |
| CN-115710251-B | Medullary differentiation factor 88 inhibitor and preparation method and application thereof | 杭州医学院 | 2024-05-28 | — | — | CN | disclosed |
| CN-115710251-A | Myeloid differentiation factor 88 inhibitor and preparation method and application thereof | 杭州医学院 | 2023-02-24 | — | — | CN | disclosed |