Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30206519 | 0.83 | TAAR1 (0.52) | RAB9A | |
| SCHEMBL30206419 | 0.80 | RAB9A (0.44) | RAB9ANOS1NOS2TP53S1PR1 | |
| SCHEMBL30206432 | 0.77 | RAB9A (0.42) | RAB9A | |
| SCHEMBL38651740 | 0.75 | RAB9A (0.46) | RAB9ANOS1NOS2TP53S1PR1 | |
| SCHEMBL30206408 | 0.74 | RAB9A (0.56) | RAB9ATP53MEN1NPC1KMT2A | |
| SCHEMBL3454955 | 0.73 | TP53 (0.67) | RAB9ATP53HTTMEN1NPC1 | |
| SCHEMBL16462690 | 0.73 | HTT (0.59) | RAB9ATP53S1PR1HTTMEN1 | |
| SCHEMBL30206496 | 0.73 | TAAR1 (0.49) | RAB9A | |
| SCHEMBL2105805 | 0.71 | RAB9A (0.53) | RAB9ATP53RORCHTTMEN1 | |
| SCHEMBL38651720 | 0.71 | RAB9A (0.53) | RAB9ATP53MEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392412-A1 | ABAD INHIBITOR COMPOUNDS | University Court of The University of St Andrews (GB) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023026060-A1 | ABAD INHIBITOR COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2023-03-02 | — | — | WO | disclosed |