Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | STS | P08842 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23783189 | 1.00 | PTPN2 (0.58) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL30738809 | 0.95 | PTPN2 (0.52) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL19617379 | 0.89 | TP53 (0.63) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL3512756 | 0.86 | ALDH1A1 (0.55) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL13060443 | 0.84 | PTPN2 (0.62) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL23783425 | 0.83 | PTPN2 (0.54) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL30207453 | 0.83 | PTPN2 (0.54) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL14447471 | 0.81 | PTPN2 (0.62) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL21392497 | 0.81 | PTPN2 (0.56) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL3171133 | 0.80 | PTPN2 (0.58) | PTPN2PTPN1PTPN6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4114392-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | C4 Therapeutics, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |