Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 7/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23783392 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTLMNATHRB | |
| SCHEMBL30255499 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPTLMNATHRB | |
| SCHEMBL31701825 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAPTLMNATHRB | |
| SCHEMBL31334845 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTLMNATHRB | |
| SCHEMBL994347 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KMT2AMAPTLMNATHRB | |
| SCHEMBL29536266 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KMT2AMAPTLMNATHRB | |
| SCHEMBL29197802 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL29179922 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KMT2AMAPTLMNATHRB | |
| SCHEMBL10036179 | 0.76 | PDK4 (0.51) | ALDH1A1MAPTLMNAGRM5GRM1 | |
| SCHEMBL29535433 | 0.76 | PDK4 (0.51) | ALDH1A1MAPTLMNAGRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823124-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-115279370-B | Compounds for targeted degradation of BRD9 | C4医药公司 | 2025-01-10 | — | — | CN | disclosed |
| EP-4114392-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | C4 Therapeutics, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |