Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | PPIA | P62937 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782118 | 1.00 | NPC1 (0.68) | NPC1RAB9APOLBCASP3PTPN1 | |
| Formic Acid SCHEMBL27606526 | 0.94 | NPC1 (0.61) | NPC1RAB9APOLBCASP3PTPN1 | |
| Formic Acid Methyl Ester SCHEMBL27606485 | 0.90 | NPC1 (0.60) | NPC1RAB9APOLBCASP3PTPN1 | |
| SCHEMBL3787582 | 0.88 | NPC1 (0.61) | NPC1RAB9APOLBCASP3PTPN1 | |
| SCHEMBL3786444 | 0.87 | NPC1 (0.68) | NPC1RAB9APOLBCASP3PTPN1 | |
| SCHEMBL14793789 | 0.85 | NPC1 (0.57) | NPC1RAB9APOLBCASP3MEN1 | |
| SCHEMBL4329901 | 0.84 | MEN1 (0.52) | NPC1RAB9ACASP3PTPN1MEN1 | |
| SCHEMBL3789239 | 0.84 | MEN1 (0.60) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL3786672 | 0.84 | MGLL (0.60) | NPC1RAB9APOLBPTPN1MEN1 | |
| SCHEMBL30207791 | 0.83 | MGLL (0.55) | NPC1RAB9APOLBCASP3P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850119-A | Synthetic method of 2-chloro aromatic amine compound | 南昌大学 | 2023-03-28 | — | — | CN | disclosed |