Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 11/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19667195 | 1.00 | PRMT5 (0.49) | PRMT5WDR77PIK3CDGPR119 | |
| SCHEMBL19667191 | 0.90 | PRMT5 (0.52) | PRMT5WDR77PIK3CDGPR119 | |
| SCHEMBL30208020 | 0.90 | PRMT5 (0.52) | PRMT5WDR77PIK3CDGPR119 | |
| SCHEMBL20873498 | 0.90 | PRMT5 (0.52) | PRMT5WDR77 | |
| SCHEMBL19667210 | 0.85 | PRMT5 (0.65) | PRMT5WDR77GPR119 | |
| SCHEMBL19667549 | 0.84 | GPR119 (0.37) | PRMT5WDR77PIK3CDGPR119 | |
| SCHEMBL30207849 | 0.84 | GPR119 (0.37) | PRMT5WDR77PIK3CDGPR119 | |
| SCHEMBL30208003 | 0.81 | PRMT5 (0.68) | PRMT5WDR77GPR119 | |
| SCHEMBL19667332 | 0.81 | PRMT5 (0.68) | PRMT5WDR77GPR119 | |
| SCHEMBL30501364 | 0.81 | PRMT5 (0.68) | PRMT5WDR77GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890797-B | Substituted carbon nucleoside derivatives useful as anticancer agents | 辉瑞公司 | 2023-02-28 | — | — | CN | disclosed |