Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19667511 | 1.00 | KDM1A (0.44) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL19679336 | 0.84 | MAPT (0.43) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL20873491 | 0.78 | MEN1 (0.46) | MAPTMAPK1TDP1L3MBTL1CFD | |
| SCHEMBL873500 | 0.77 | DRD2 (0.54) | HTR2CHTR1A | |
| SCHEMBL14157832 | 0.77 | DRD2 (0.54) | HTR2CHTR1A | |
| SCHEMBL4839911 | 0.77 | DRD2 (0.54) | HTR2CHTR1A | |
| SCHEMBL873501 | 0.77 | DRD2 (0.54) | HTR2CHTR1A | |
| SCHEMBL4749715 | 0.76 | HTR1B (0.44) | HTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL9825244 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL8823809 | 0.76 | DRD2 (0.53) | HTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890797-B | Substituted carbon nucleoside derivatives useful as anticancer agents | 辉瑞公司 | 2023-02-28 | — | — | CN | disclosed |