Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.56 |
| ▸ | FEN1 | P39748 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMO | Q99835 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373805 | 0.88 | POLB (1.00) | POLBALDH1A1TP53L3MBTL1HTT | |
| SCHEMBL28456106 | 0.81 | POLB (0.70) | POLBALDH1A1TP53L3MBTL1HTT | |
| SCHEMBL11593314 | 0.79 | POLB (0.81) | POLBALDH1A1TP53L3MBTL1HTT | |
| SCHEMBL8372435 | 0.78 | POLB (0.78) | POLBALDH1A1TP53L3MBTL1HTT | |
| SCHEMBL11822574 | 0.78 | POLB (0.78) | POLBALDH1A1TP53L3MBTL1HTT | |
| SCHEMBL8856838 | 0.77 | POLB (0.77) | POLBALDH1A1TP53L3MBTL1HTT | |
| SCHEMBL11591182 | 0.76 | POLB (0.75) | POLBALDH1A1TP53L3MBTL1HTT | |
| SCHEMBL8731612 | 0.76 | POLB (0.75) | POLBALDH1A1TP53L3MBTL1HTT | |
| SCHEMBL19893245 | 0.75 | POLB (0.67) | POLBALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL1882550 | 0.74 | POLB (0.72) | POLBALDH1A1TP53L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111548320-B | 1,3,4-oxadiazole hydrazide compounds and preparation method and application thereof | 贵州大学 | 2023-03-24 | — | — | CN | disclosed |