Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373805 | 0.84 | POLB (1.00) | POLBALDH1A1RAB9AHTTTP53 | |
| SCHEMBL30208659 | 0.81 | POLB (0.78) | POLBALDH1A1NPC1RAB9AHTT | |
| SCHEMBL11593314 | 0.79 | POLB (0.81) | POLBALDH1A1NPC1RAB9AHTT | |
| SCHEMBL11822574 | 0.77 | POLB (0.78) | POLBALDH1A1NPC1RAB9AHTT | |
| SCHEMBL8856838 | 0.77 | POLB (0.77) | POLBALDH1A1HTTTP53L3MBTL1 | |
| SCHEMBL5318618 | 0.77 | CES2 (0.65) | POLBALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL13479861 | 0.75 | POLB (0.62) | POLBALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL20287824 | 0.75 | SMN1; SMN2 (0.59) | POLBALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL20747778 | 0.75 | CES2 (0.52) | POLBALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL28002678 | 0.74 | POLB (0.50) | POLBALDH1A1TP53MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111548320-B | 1,3,4-oxadiazole hydrazide compounds and preparation method and application thereof | 贵州大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-111548320-A | 1, 3, 4-oxadiazole hydrazide compounds and preparation method and application thereof | 贵州大学 | 2020-08-18 | — | — | CN | disclosed |