Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 5/20 | 0.98 |
| ▸ | GNB1 | P62873 | 5/20 | 0.98 |
| ▸ | P2RY4 | P51582 | 9/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.76 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.62 |
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.62 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.61 |
| ▸ | CDK2 | P24941 | 2/20 | 0.61 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.61 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778373 | 0.99 | GNG2 (1.00) | GNG2GNB1P2RY4CYP1A2CYP2C9 | |
| SCHEMBL7166757 | 0.98 | GNG2 (0.98) | GNG2GNB1P2RY4CYP1A2CYP2C9 | |
| SCHEMBL8640965 | 0.91 | GNG2 (0.85) | GNG2GNB1P2RY4CYP1A2CYP2C9 | |
| SCHEMBL790823 | 0.90 | GNG2 (0.83) | GNG2GNB1P2RY4CYP1A2CYP2C9 | |
| SCHEMBL790523 | 0.89 | GNG2 (0.79) | GNG2GNB1P2RY4CYP1A2CYP2C9 | |
| SCHEMBL792757 | 0.89 | GNG2 (0.79) | GNG2GNB1P2RY4CYP1A2CYP2C9 | |
| SCHEMBL791497 | 0.89 | GNG2 (0.85) | GNG2GNB1P2RY4CYP1A2CYP2C9 | |
| SCHEMBL791019 | 0.89 | GNG2 (0.85) | GNG2GNB1P2RY4CYP1A2CYP2C9 | |
| SCHEMBL29357302 | 0.89 | GNG2 (0.85) | GNG2GNB1P2RY4CYP1A2CYP2C9 | |
| SCHEMBL8639112 | 0.89 | GNG2 (0.81) | GNG2GNB1P2RY4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129653-B1 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2017-05-17 | — | — | EP | disclosed |
| US-20100210654-A1 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN (DE) | 2010-08-19 | — | — | US | disclosed |
| EP-1967513-A1 | Novel P2Y12 receptor antagonists | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2008-09-10 | — | — | EP | disclosed |
| US-6554874-B1 | Mixture of a bis(anthraquinonyl) substituted blue triazine dye; disazo triazine yellow- or orange dye; and disazo hydroxy-containing triazine red dye | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210654-A1 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | P2RY12, P2RY11, P2RY13 | GNG2 233/4885GNB1 314/4885P2RY4 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.