Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.71 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.71 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.71 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.71 |
| ▸ | NCF1 | P14598 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | F2R | P25116 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3529700 | 0.87 | HDAC8 (0.73) | HDAC8HDAC6HDAC2HDAC1HDAC3 | |
| SCHEMBL3529705 | 0.87 | HDAC8 (0.73) | HDAC8HDAC6HDAC2HDAC1HDAC3 | |
| SCHEMBL3533684 | 0.83 | HDAC8 (1.00) | HDAC8HDAC6HDAC2HDAC1HDAC3 | |
| SCHEMBL3533682 | 0.83 | HDAC8 (1.00) | HDAC8HDAC6HDAC2HDAC1HDAC3 | |
| SCHEMBL29597329 | 0.83 | HDAC8 (0.66) | HDAC8HDAC6HDAC2HDAC1HDAC3 | |
| SCHEMBL30209643 | 0.82 | PFKFB3 (0.52) | HDAC8HDAC6HDAC2HDAC1HDAC3 | |
| SCHEMBL23761162 | 0.81 | HDAC6 (0.65) | HDAC8HDAC6HDAC2HDAC1HDAC3 | |
| SCHEMBL23751539 | 0.80 | EGFR (0.71) | HDAC8HDAC6HDAC2HDAC1HDAC3 | |
| SCHEMBL16547129 | 0.80 | PFKFB3 (0.71) | HDAC8HDAC6HDAC2HDAC1HDAC3 | |
| SCHEMBL30209650 | 0.79 | BACE1 (0.47) | HDAC8HDAC6HDAC2HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745898-A | Aromatic acrylamide-triazole compound, and preparation method and application thereof | 许昌学院 | 2023-03-07 | — | — | CN | disclosed |